DefenAge 24/7 Barrier Balance Creme PRO

A daily facial moisturizer created to replenish hydration and support a balanced, resilient skin barrier. It helps improve softness, comfort and surface texture without feeling excessively heavy, making it useful for both morning and evening routines. The cream can be paired with corrective serums to reduce dryness and keep the complexion looking smooth and healthy.

$108.00

Available at

A more targeted approach to hydration, comfort and barrier balance

A daily facial moisturizer created to replenish hydration and support a balanced, resilient skin barrier. It helps improve softness, comfort and surface texture without feeling excessively heavy, making it useful for both morning and evening routines. The cream can be paired with corrective serums to reduce dryness and keep the complexion looking smooth and healthy.

24/7 Barrier Balance Cream combines DefenAge Age-Repair Defensins® with daily moisturization and barrier support. It is designed to improve visible texture, brightness and comfort while helping the skin maintain a more balanced moisture environment.

Product highlights

  • Provides morning-and-evening hydration without an excessively occlusive finish.
  • Supports the look of smoother texture and a more even, luminous complexion.
  • Age-Repair Defensins are incorporated into a barrier-conscious daily cream.
  • Works as the moisturizing step within a DefenAge professional regimen.

Recommended use

Apply to slightly moist face and neck after cleansing and treatment products, following the product’s recommended order. Use morning and evening. Finish the daytime routine with broad-spectrum sunscreen.

A good fit for

Patients wanting a daily moisturizer that addresses dryness and barrier balance while complementing age-supportive treatments.

Where it fits in your regimen

Use a lighter amount in humid conditions and a more generous amount when dry. Your provider may place certain DefenAge serums after the moisturizer, so follow the recommended sequence rather than assuming the usual serum-first order.

Follow the current product label and any personalized recommendations from The Dermatology Clinic. Stop use and contact the clinic if significant or persistent irritation develops. Product availability can change by location.